Multifactorial Regulation of Ovarian Function in Teleosts

Fuzzen, M, N.J. Bernier and G.Van Der Kraak 2011. Differential effects of 17β-estradiol and 11-ketotestosterone on the endocrine stress response in zebrafish (Danio rerio). General and Comparative Endocrinology 70: 365-373.

Fuzzen, M. N.J. Bernier and G. Van Der Kraak. 2011. Stress and Reproduction. In: D.O Norris and K. H. Lopez, Eds. Hormones and Reproduction in Vertebrates. Volume 1:Fishes Elsevier, pp.103-117.

Van Der Kraak, G., and A. L Lister. 2011. The inhibitory control of oocyte maturation in the zebrafish: the role of the G-protein coupled estrogen receptor and epidermal growth factor. Biology of Reproduction 85: 6-8.

Eykelbosh, A.J. and G. Van Der Kraak. 2010. A role for the lysosomal protease cathepsin B in zebrafish follicular apoptosis. Comparative Biochemistry and Physiology A. 156: 218-223.

Fuzzen, M, G.Van Der Kraak and N.J. Bernier. 2010. Stirring up new ideas about the regulation of the hypothalamic-pituitary-interrenal axis in zebrafish (Danio rerio). Zebrafish 7: 349-358

Nelson, S.N.and G,Van Der Kraak. 2010.Characterization and regulation of the insulin-like growth factor (IGF) system in the zebrafish (Danio rerio) ovary. General and Comparative Endocrinology 168: 111-120

Nelson, S.N.and G,Van Der Kraak. 2010. The role of the insulin-like growth factor (IGF) system in zebrafish (Danio rerio) ovarian development. General and Comparative Endocrinology 168: 103-110.

Van Der Kraak, G. 2009. The GnRH system and the neuroendocrine regulation of reproduction. In: N. Bernier, G. Van Der Kraak, A.P. Farrell and C. Brauner, Eds. Fish Physiology Volume 28 Fish Neuroendocrinology pp 115-149. [NSERC DG]

Lister, A. and G. Van Der Kraak. 2009. Regulation of prostaglandin synthesis in the ovaries of sexually-mature zebrafish. Molecular Reproduction and Development 76: 1064-1075.

Lister, A., C. Regan, J. Van Zwol and G. Van Der Kraak. 2009. Inhibition of egg production in zebrafish by fluoxetine and municipal effluents: a mechanistic evaluation. Aquatic Toxicology 95: 320-329.

Lister, A.L. and G. Van Der Kraak. 2008. An investigation into the role of prostaglandins in zebrafish oocyte maturation and ovulation. General and Comparative Endocrinology 59: 46-57.

Alsop, D.H., J.Matsumoto, S.B. Brown and G. Van Der Kraak. 2008. Retinoid requirement in the reproduction of zebrafish. General and Comparative Endocrinology 156: 51-62.

Alsop, D.H., S.B. Brown and G. Van Der Kraak. 2007. The effects of copper and benzo[a]pyrene on retinoids and reproduction in zebrafish. Aquatic Toxicology 82:281-295.

Ings, J.S and G, Van Der Kraak. 2006. Characterization of the expression of StAR and steroidogenic enzymes in zebrafish ovarian follicles. Molecular Reproduction and Development 73: 943-954.

Wood, A.W., D.M. Janz and G. Van Der Kraak. 2005. Cell death; investigation and application in fish toxicology. Biochemistry and Molecular Biology of Fishes, 6; Environmental Toxicology, T.P. Mommsen and T. Moon, eds. pp. 303-328.

Alsop, D., G.J. Van Der Kraak, S. B. Brown and J. G. Eales. 2005. The biology and toxicology of retinoids in fish. Biochemistry and Molecular Biology of Fishes, 6; Environmental Toxicology, T.P. Mommsen and T. Moon, eds. pp. 413-428.

Wood, A.W., J. Matsumoto, and G. Van Der Kraak. 2004. Thyroglobulin type-1 domain protease inhibitors exhibit specific expression in the cortical ooplasm of vitellogenic rainbow trout oocytes. Molecular Reproduction and Development 69: 205-214.

Wood, A.W., and G. Van Der Kraak. 2003. Yolk proteolysis in rainbow trout oocytes after serum-free culture: evidence for a novel biochemical mechanism of atresia in oviparous vertebrates. Molecular Reproduction and Development 65:219-227.

Calp, M.K., J.A. Matsumoto and G. Van Der Kraak. 2003. Activin and transforming growth factor-ß as local regulators of ovarian function in the goldfish. General and Comparative Endocrinology 132: 142-150.

Lister, A. and G. Van Der Kraak. 2002. Modulation of goldfish testicular testosterone production in vitro by tumor necrosis factor, interleukin-1, and macrophage conditioned media. Journal of Experimental Zoology 292:477-486.

Wood, A. and G. Van Der Kraak. 2002. Inhibition of apoptosis in vitellogenic ovarian follicles of rainbow trout (Oncorhynchus mykiss) by salmon gonadotropin, epidermal growth factor and 17 ß-estradiol. Molecular Reproduction and Development 61:511-518.

Wood, A. and G. Van Der Kraak. 2001. Apoptosis and ovarian function: novel perspectives from the teleosts. Biology of Reproduction. 64: 264-271.

Alsop, D., S. Brown and G. Van Der Kraak. 2001. Development of a retinoic acid receptor binding assay with rainbow trout tissue: characterization of retinoic acid binding, receptor tissue distribution and developmental changes. General and Comparative Endocrinology 123: 254-267.

Alsop, D., S. Brown and G. Van Der Kraak. 2001. Development of a retinoic acid receptor binding assay with rainbow trout tissue: characterization of retinoic acid binding, receptor tissue distribution and developmental changes. General and Comparative Endocrinology 123: 254-267.

Evaluation of Reproductive Fitness in Fish

i. General reproductive biology

Stacey, N.E. G.J. Van Der Kraak and K. H.Olsen, Male primer endocrine responses to preovulatory females: field studies in Swedish cyprinids. Journal of Fish Biol. 80: 147-165.

Desjardins, J.K., J.L. Fitzpatrick, K.A. Stiver, G. Van Van Der Kraak and S. Balshine. 2011. Lunar and diurnal cycles in reproductive physiology and behaviour in a natural population of cooperatively breeding fish. Journal of Zoology 285: 66-73.

Lister, A.L., G. Van Der Kraak, R.Rutherford, D. MacLatchy. 2011. Fundulus heteroclitus: Ovarian reproductive physiology and the impact of environmental contaminants. Comp Biochem Physio. C. 154: 278-287.

O’Connor, C.M., K.M. Gilmour, G. Van Der Kraak, S.J. Cooke. 2011. Circulating androgens are influenced by parental nest defense in a wild teleost fish. Journal of Comparative Physiology – A. 197: 711-715.

O’Connor, C.M., C. Y. Yick, K.M. Gilmour, G. Van Der Kraak, S.J. Cooke. 2011. The glucocorticoid stress response is attenuated but unrelated to reproductive investment during parental care in a teleost fish. General and Comparative Endocrinology 170: 215-221.

Dey, C.J., C. M. O’Connor, K. M. Gilmour, G. Van Der Kraak, S. J. Cooke. 2010. Behavioral and physiological responses of a wild teleost fish to cortisol and androgen manipulation during parental care. Hormones and Behavior 58: 599-605.

Hanson, K., C.M. O’Connor, G. Van Der Kraak and S.J. Cooke. 2009. Paternal aggression towards a brood predator during parental care in wild smallmouth bass is not correlated with biochemical or endocrine status. Hormones and Behavior 55:495-499.

O’Connor, C.M., K.M. Gimour, R. Aringhaus, G. Van Der Kraak and S.J. Cooke. 2009. Stress and parental care in a wild teleost: Insights from exogenous supraphysiological cortyisol implants. Physiological and Biochemical Zoology 82: 709-19.

Desjardins, J.K., K.A. Stiver, J.L. Fitzpatrick, N. Milligan, G.J. Van Der Kraak and S. Balshine. 2008. Behavioral and hormonal correlates of sex and status in a cooperatively breeding fish (Neolamrologus pulcher). Behavioural Ecology and Sociobiology 62:785-794.

Desjardins, J.K., J.L. Fitzpatrick, K.A. Stiver, N. Milligan, G.J. Van Der Kraak and S. Balshine 2008. Costs and benefits of polygyny in the cichlid,Neolamprologus pulcher. Animal Behaviour 75: 1771-1779.

ii Reproductive Toxicology

Kovacs, T., P.Martel, B. O’Connor, J. Parrott, M. McMaster, G. Van Der Kraak, D. MacLatchy, M.van den Heuvel and L. M. Hewitt. 2011. Kraft mill effluent survey: Leads toward best management practices for eliminating effects on fish reproduction. Environmental Toxicology and Chemistry 30:1421-1429.

Martel, P.H., T. G. Kovacs, B. I. O’Connor, S. Semeniuk, L. M Hewitt, D. MacLatchy, M. E. McMaster, J. L. Parrott, M. R. van den Heuvel and Glen J. Van Der Kraak. 2011. Effluent monitoring at a bleached kraft mill: Directions for best management practices for eliminating effects on fish reproduction. Journal of Toxicology and Environmental Health Part A. 46:833-843.

Oakes, K., A.Coors, B. I. Escher, K. Fenner, J. Garric, M. Gust, T. Knacker, A. Küster, C. Kussatz, C. D. Metcalfe, S. Monteiro, T.W. Moon, J. A. Mennigen, J. Parrott, A.R.R. Péry, M. Ramil, I. Roennefahrt J.V Tarazona, P.Sánchez-Argüello, T.A Ternes, V. L Trudeau, T. Boucard, G.J. Van Der Kraak and M.R Servos. 2010. An Environmental Risk Assessment for the Serotonin Re-uptake Inhibitor Fluoxetine – A Case Study Utilizing the European Risk Assessment Framework. Integrated Environmental Assessment and Management. 6 Supplement 1: 524-539.

Orrego, R., M. McMaster, G. Van Der Kraak and D. Holdway. 2010. Effects of pulp and paper mill effluent extractives on aromatase CYP19a gene expression and sex steroidlevels in juvenile triploid rainbow trout. Aquatic Toxicology 97:353-360.

Parrott, J.L., L M Hewitt, T. G. Kovacs, D.L. MacLatchy, P.H. Martel, M. R. van den Heuvel, G. J. Van Der Kraak, and M. E. McMaster. 2010. Responses in a fathead minnow (Pimephales promelas) lifecycle test and in wild white sucker (Catostomus commersoni) exposed to a Canadian bleached kraft mill effluent Water Quality Research J Canada 2010: 45: 187-200.

van den Heuvel, M. P. H Martel, T. G. G Kovacs, D.L, MacLatchy, G.J. Van Der Kraak, J.L. Parrott, M.E. McMaster, B. O’Connor, S.D. Melvin and L. M. Hewitt. 2010. Evaluation of short-term fish reproductive bioassays for predicting effects of a Canadian bleached kraft mill effluent. Water Quality Research J Canada 45: 175-186.

Orrego, R., M. McMaster, G. Van Der Kraak and D. Holdway. 2010. Effects of pulp and paper mill effluent extractives on aromatase CYP19a gene expression and sex steroid levels in juvenile triploid rainbow trout. Aquatic Toxicology doi:10.1016/j.aquatox.2010.01.002

Hewitt, M., T. Kovacs, M. Dube, D. MacLatchy, P. Martel, M. McMaster, M. Paice, J. Parrott, M. van den Heuvel and G. Van Der Kraak. 2008. Altered reproduction in fish exposed to pulp and paper mill effluents: Role of individual compounds and mill operating conditions. Environmental Toxicology and Chemistry 27: 682-697.

Perkins, E., N. Denslow, J. K. Chipman, P.D. Guiney, J.R. Oris, H. Poynton, P.Y. Robidoux, R. Scroggins and G. Van Der Kraak. 2007. Application of genomics to assessment of the ecological risk of complex mixtures. In: Genomics in regulatory ecotoxicology : Applications and Challenges. G.T. Ankley, A.L. Miracle, E.J. Perkins and G.P. Daston, eds. pp. 87-121.

Leanos-Castaneda, G. Van Der Kraak, R. Rodriquez-Canul and G. Gold. 2007.Endocrine disruption mechanism of o,p’-DDT in mature male Tilapia (Oreochromis niloticus). Toxicology and Applied Pharmacology 221:158-167.

Leanos-Castaneda and G. Van Der Kraak. 2007. Functional characterization of estrogen receptor subtypes, ERa and ERβ, mediating vitellogenin production in the liver of rainbow trout. Toxicology and Applied Pharmacology 224: 116-125.

Marlatt, V.L., L.M. Hewitt and G. Van Der Kraak. 2006. Utility of in vitro test methods to assess the activity of xenoestrogens in fish. Environmental Toxicology and Chemistry 25: 3204-3212.

Oakes, K.D., L.A. Tremblay and G.J. Van Der Kraak. 2005. Short-term lab exposures of immature rainbow trout (Oncorhynchus mykiss) to sulphite and kraft pulp mill effluents: effects on oxidative stress and circulating sex steroids. Environmental Toxicology and Chemistry 24: 1451-1461.

Oakes, K.D., P.K. Sibley, J.W. Martin, D.D. MacLean, K.R. Solomon, S.A. Mabury and G.Van Der Kraak. 2005. Short-term exposures of fish to perfluoroctane sulfonate (PFOS): effects on fatty acyl-CoA oxidase, oxidative stress and circulating sex steroids. Environmental Toxicology and Chemistry 24: 1172-1181.

Oakes, K.D., L.M. Hewitt, M.E. McMaster, C.Wood, K.R. Munkittrick and G. J, Van Der Kraak. 2005. Oxidative stress and sex steroid levels in fish following short term exposure to pulp mill effluents. Journal of Toxicology and Environmental Health Part A, 68: 267-285.

MacLatchy, D.M., K. L. Gormley, R.E.M. Ibey, R.L. Sharpe, K. S. Shaughnessey, S.C. Courtenay, M.G. Dube and G. Van Der Kraak. 2005. A short term Mummichog (Fundulus heteroclitus) bioassay to assess endocrine responses to hormone-active compounds and mixtures. In Techniques in Aquatic Toxicology Vol. 2. (G. Ostrander, Ed.). pp. 55-91.

McMaster, M.E., L.M. Hewitt, G.R. Tetreault, T. Janoscik, C. Boyko, L. Peters, J.L. Parrott, G.J. Van Der Kraak, C.B. Portt, K. J. Kroll, and N.D. Denslow. 2005. Detailed endocrine Assessments of wild fish in the Northern River Basins, Alberta in comparison to EEM monitored endpoints. Water Quality Research Journal of Canada 40: 299-314.

Hewitt, M., R. Schryer, A. Pryce, A. Belknap, B. Firth and G. Van Der Kraak. 2005. Hormonally-active substances are accumulated by wild white sucker (Catostomus commersoni) exposed to effluents discharged to the Wabigoon River. Water Quality Research Journal of Canada 40: 315-327.

Sharpe, R.L., D. L. MacLatchy, S.C. Courtnay, and G. Van Der Kraak. 2004. Effects of a model androgen (methyl testosterone) and a model anti-androgen (cyproterone acetate) on reproductive endocrine endpoints in a short-term adult mummichog (Fundulus heteroclitus) bioassay. Aquatic Toxicology 67: 203-215.

Oakes, K.D., P.K. Sibley, K.R. Solomon, S.A. Mabury and G.J. Van Der Kraak. 2004. Impact of perfluorooctanoic acid (PFOA) on fathead minnow (Pimpephales promelas) fatty acyl-CoA oxidase activity, circulating steroids and reproduction in outdoor mesocosms. Environmental Toxicology and Chemistry 23: 1912-1919.

Oakes, K.D., M.E. McMaster and G. Van Der Kraak. 2004. Oxidative stress responses in longnose sucker (Catostomas catostomas) exposed to pulp and paper mill and municipal sewage effluents. Aquatic Toxicology 67: 255-271.

Pryce-Hobby, A.C., M.E. McMaster, L.M. Hewitt and G. Van Der Kraak. 2003. The effects of pulp mill effluent on the sex steroid binding protein in white sucker (Catostomus commersoni) and longnose sucker (C. catostomus) Comparative Biochemistry and Physiology 134: 241-250.

Oakes, K.D. and G. Van Der Kraak. 2003. Utility of the TBARS assay in detecting oxidative stress in feral white sucker (Catostomus commersoni) populations exposed to pulp and paper mill effluent. Aquatic Toxicology 63:447-463.

Oakes, K.D., M.E. McMaster, A.C. Pryce, K.R. Munkittrick, C.B. Portt, L.M. Hewitt, G.J. Van Der Kraak. 2003. Oxidative stress and bioindicators of reproductive function in pulp and paper mill effluent exposed white sucker. Toxicological Sciences 74: 51-65.

MacLatchy, D.L., S.C. Courtenay, C.D. Rice and G. Van Der Kraak. 2003. Development and evaluation of a short-term reproductive endocrine bioassay with the estuarine mummichog, (Fundulus heteroclitus). Environmental Toxicology and Chemistry 22: 996-1008.

Levesque, H.M., J. Dorval, A. Honteal, G. Van Der Kraak, and P.G.C. Campbell. 2003. Hormonal, morphological and physiological responses of yellow perch (Perca flavescens) to chronic environmental metal exposures. Journal of Toxicology and Environmental Health, Part A 66: 657-676.

Hewitt, L.M., A.C. Pryce, J.L. Parrott, V. Marlatt, C. Wood, K. Oakes and G. Van Der Kraak. 2003. Accumulation of ligands for aryl hydrocarbon and sex steroid receptors in fish exposed to treated effluent from a bleached sulphite/groundwood pulp and paper mill. Environmental Toxicology and Chemistry 22: 2890-2897.

Burnison, B.K., A. Hartmann, A. Lister, M.R. Servos, T. Ternes, G. Van Der Kraak. 2003. A toxicity identification evaluation (TIE) approach to study estrogenic substances in hog manure and agricultural runoff. Environmental Toxicology and Chemistry 22: 2243-2250

Alsop, D., M. Hewitt, M. Kohli, S. Brown, G. Van Der Kraak. 2003. Constituents within pulp mill effluent deplete retinoid stores in white sucker and bind to rainbow trout retinoic acid receptors and retinoid X receptors. Environmental Toxicology and Chemistry 22: 2969-2976.

Schoenfuss, H.L., J.T. Levitt, G. Van Der Kraak and P.W. Sorensen. 2002. Ten-week exposure to treated sewage discharge has relatively minor, variable effects on reproductive behavior and sperm production in goldfish. Environmental Toxicology and Chemistry 21:2185-2190.

WHO/IPCS. 2002. Global Assessment of the State of the Science of Endocrine Disruptors. Eds T. Damstra, S. Barlow, A. Bergman, R. Kavlock. G.Van Der Kraak WHO/PCS/EDC/02.2 World Health Organization, Geneva, Switzerland. 180pp http://ehp.niehs.nih.gov/who/

Van Der Kraak, G., M. Hewitt, A. Lister, M.E. McMaster and K.R. Munkittrick. 2001. Endocrine toxicants and reproductive success in fish. Human and Ecological Risk Assessment 7: 1017-1025.

Servos, M.R. and G. Van Der Kraak (Editors). 2001. Endocrine disrupting substances in the Canadian Environment. Water Quality Research Journal of Canada. 36.pp. 171-346.

McMaster, M.E., J.J. Jardine, G. Ankley, W.H. Benson, M. Greely, T. Gross, L. Guillette, D. MacLatchy, E. Orlando, G. Van Der Kraak and K.R. Munkittrick. 2001. An interlaboratory study on the use of steroid hormone in examining endocrine disruption. Environmental Toxicology and Chemistry 20: 2081-2087.

Lister, A. and G.J. Van Der Kraak. 2001. Endocrine disruption: why is it so complicated? Water Quality Research Journal of Canada 36: 175-188.

Janz, D.M., M.E. McMaster, L.P. Weber, K.R. Munkittrick and G. Van Der Kraak. 2001. Recovery of ovary size, follicle cell apoptosis and HSP70 expression in fish exposed to bleached kraft pulp mill effluent. Canadian Journal of Fisheries and Aquatic Sciences 58: 620 625.

Evanson, M. and G. Van Der Kraak. 2001. Stimulatory effects of selected PAHs on testosterone production in goldfish and rainbow trout and possible mechanisms of action. Comparative Biochemistry and Physiology 130: 249-258.

Wells, K. L. and G. Van Der Kraak. 2000. Differential binding of endogenous steroids and environmental chemicals to androgen receptors in rainbow trout and goldfish. Environmental Toxicology and Chemistry 19: 2059-2065.

Hewitt, L.M., J.L. Parrott, K.L. Wells, M.K. Calp, S. Biddiscombe, M.E. McMaster, K.R. Munkittrick and G. Van Der Kraak. 2000. Characteristics of ligands for the Ah receptor and sex steroid receptors in hepatic tissues of fish exposed to bleached kraft mill effluent. Environmental Science and Technology 34: 4327-4334.

iii. Impacts of Oil Sands Wastes

Kavanagh, R.J., R.A. Frank, K. D. Oakes, M. R, Servos, R. F. Young, P. M. Fedorak, M. MacKinnon, K. R. Solomon, D. G. Dixon and G. Van Der Kraak. 2011. Fathead minnow (Pimephales promelas) reproduction is impaired in aged oil sands process-affected waters. Aquatic Toxicology 101: 214-220.

van den Heuvel, M., N. Hogan, S. Roloson and G. Van Der Kraak. Reproductive development of yellow perch (Perca flavescens) exposed to oil sands-affected waters. Environmental Toxicology and Chemistry Accepted Nov 2011; 25 typed p; 4 Figs.

Gosselin P, S.E. Hrudey, A.M. Naeth, A Plourde, R. Therrien, G. Van Der Kraak and Z. Xu, 2010. Environmental and Health Impacts of Canada’s Oil Sands Industry. Ottawa, Ontario: Royal Society of Canada (Dec 2010). 436pp. http://www.rsc.ca/documents/expert/RSC%20report%20complete%20secured%209Mb.pdf

Frank, R., K. Fischer, R. Kavanagh, K. Burnison, G. Arsenault, J. Headley, K. Peru, G. Van Der Kraak and K. Solomon. 2009. Proposing narcosis as the mode of action for oil sand naphthenic acids: Why bigger is better”. Environmental Science and Technology 43:266-271.

Kavanagh, B. K.Burnison, R. A. Frank, K.R. Solomon and G. Van Der Kraak.2009. Detecting oil sands process-affected waters in the Alberta oil sands region using synchronous fluorescence spectroscopy. Chemosphere 76: 120-126.

Lister, A., V. Nero, A. Farwell, D.G. Dixon and G. Van Der Kraak. 2008. Reproductive and stress hormone levels in goldfish (Carassius auratus) exposed to oilsands process-affected water. Aquatic Toxicology 87: 170-177.

Frank, R., R. Kavanagh, B. K. Burnison, G. Arsenault, J. V. Headley, K. M. Peru, G. Van Der Kraak and K. R. Solomon. 2008. Toxicity assessment of collected fractions from an extracted naphthenic acid mixture. Chemopshere 72: 1309-1314.

Nero, V., A. Farwell, A. Lister, G. Van Der Kraak, L.E.J. Lee, T. Van Meer, M.D. MacKinnon and D. G. Dixon. 2005. Gill and liver histopathological changes in yellow perch (Perca flavescens) and goldfish (Carassius auratus) exposed to oil sands process-affected water. Ecotoxicology and Environmental Safety 63: 365-377.

iv. Early Run Mortality in Sockeye Salmon

Cooperman, M.S., S. G. Hinch, G. T. Crossin, S. J.Cooke, D.A. Patterson, I. Olssen, A. Otto, A.G. Lotto, D. Welch, J. M. Shrimpton, G. Van Der Kraak, and A.P Farrell. 2010. Effects of experimental manipulations of salinity and maturational status on the physiological condition and mortality of homing adult sockeye salmon held in a laboratory. Physiological Zoology 83: 459-472.

Crossin G.T., S.G.Hinch SG, S.J. Cooke, D.A. Patterson, A.G. Lotto, G. Van Der Kraak, Y. Zohar,, U. Klenke and A.P. Farrell. 2010. Testing the synergistic effects of GnRH and testosterone on the reproductive physiology of pre-adult pink salmon Oncorhynchus gorbuscha. J.Fish Biol. 76:112-128.

Donaldson, M.R., S.G. Hinch,, D.A. Patterson, A.P. Farrell, J.M. Shrimpton, K.M., Miller-Saunders, D., Robichaud, J. Hills, K.A. Hruska, K.C. Hanson, K.K. English, G. Van Der Kraak and SJ. Cooke. 2010. Physiological condition differentially affects the behaviour and survival of two populations of sockeye salmon during their freshwater spawning migration. Physiological and Biochemical Zoology 83: 446-458.

Crossin, G.T., S.G. Hinch, S.J. Cooke, D.W. Welch, D.A. Patterson, S.R.M. Jones, A.G. Lotto, R.A. Leggatt, M.T. Mathes, J.M. Shrimpton, G. Van Der Kraak, and A.P. Farrell. 2008. Exposure to high temperature influences the behaviour, physiology, and survival of sockeye salmon during spawning migration. Canadian Journal of Zoology 86: 127-140.

Cooke, S.J., S.G. Hinch, A.P. Farrell, D.A. Patterson, K. Miller-Saunders, D.W. Welch, M.R. Donaldson, K.C. Hanson, G.T. Crossin, M.S. Cooperman, M.T. Mathes, A.G. Lotto, K.A. Hruska, I. Olsson, G.N. Wagner, R. Thomson, R. Hourston, K.K. English, S. Larsson, J.M. Shrimpton, and G. Van Der Kraak. 2008. Developing a mechanistic understanding of fish migrations by linking telemetry with physiology, behaviour, genomics and experimental biology: an interdisciplinary case study on adult Fraser River sockeye salmon. Fisheries 33: 321-338.

Cooke, S.J., G.T. Crossin, D.A. Patterson, S.G. Hinch, K.K. English, M.C. Healey, S. Macdonald, M. Shrimpton, A. Lister, G. Van Der Kraak, and A.P. Farrell. 2008. Physiological correlates of coastal arrival and river entry timing in late summer Fraser River Sockeye salmon (Oncorhynchus nerka). Behavioural Ecology 19: 747-758.

Hanson, K.C., S.J. Cooke, S.G. Hinch, G.T. Crossin, D.A. Patterson, K.K. English, M.R. Donaldson, J.M. Shrimpton, G. Van Der Kraak, and A.P. Farrell. 2008. Individual variation in migration speed of upriver migrating sockeye salmon in the Fraser River in relation to their physiological and energetic status at marine approach. Physiological and Biochemical Zoology 81: 255-268.

Crossin, G.T., S.G. Hinch, S. J. Cooke, D.W. Welch, S.D. Batten, D.A. Patterson, J.M. Shrimpton and A.P. Farrell. 2007. Behaviour and physiology of sockeye salmon homing through coastal waters to a natal river. Marine Biology 152:905-918.

Young, J.L., S.G. Hinch, S.J. Cooke, G.T. Crossin, D.A. Patterson, A.P Farrell, G. Van Der Kraak, A. Lotto, A. Lister, M.C. Healey and K. English. 2006. Physiological and energetic correlates of en route mortality for abnormally early migrating adult sockeye salmon (Oncorhynchus nerka) in the Thompson River, British Columbia. Canadian Journal of Fisheries and Aquatic Sciences 63: 1067-1077.

Cooke, S.J., S.G. Hinch, G.T. Crossin, D.A. Patterson, K.K. English, M.C. Healey, J.M. Shrimpton, G. Van Der Kraak and A.P. Farrell. 2006. Mechanistic basis of individual mortality in Pacific salmon during spawning migrations. Ecology 87: 1575-1586.

Cooke, S.J., S.G. Hinch, G.T. Crossin, D.A. Patterson, K.K. English, J.M. Shrimpton, G. Van Der Kraak, and A.P. Farrell. 2006. Physiology of individual late-run Fraser River sockeye salmon (Oncorhynchus nerka) sampled in the ocean correlates with fate during spawning migration. Canadian Journal of Fisheries and Aquatic Sciences 63:1469-1480.

Wagner, G.N., S.G. Hinch, L.J. Kuchel, A. Lotto, S.R.M. Jones, D.A. Patterson, J.S. Macdonald, G. Van Der Kraak, M. Shrimpton, K.K. English, S. Larsson, S. J. Cooke, M.C. Healey and A.P. Farrell, 2005. Metabolic rates and swimming performance of adult Fraser River sockeye salmon (Oncorhynchus nerka) after a controlled infection with Parvicapsula minibicornis. Canadian Journal of Fisheries and Aquatic Sciences 62: 2124-2133.

Cooke, S.J., G.T. Crossin , D. Patterson, K.K. English, S.G. Hinch, J.L. Young, JR.F. Alexander, M.C. Healey, G. Van Der Kraak and A.P. Farrell. 2005. Coupling non-invasive physiological assessments with telemetry to understand inter-individual variation in behaviour and survivorship of fish: development and validation of a technique. Journal of Fish Biology 67: 1342-1358.

Cooke, S.J., S.G. Hinch, A.P. Farrell, M.F. LaPointe, S.R.M. Jones, J.S. MacDonald, D. Patterson, M. C. Healey and G. Van Der Kraak, 2004. Abnormal migration timing and high enroute mortality of sockeye salmon in the Fraser River, British Columbia. Fisheries 29: 22-33.

Ecotoxicological Effects of Atrazine on Fish and Amphibians

Matsumoto, J, A.J. Hosmer, and G. Van Der Kraak, 2010. Survival, growth and iono-regulatory performance in Atlantic salmon smolts was not affected by atrazine exposure. Comparative Biochemistry and Physiology: Part C Pharmacology and Toxicology 152: 379-384.

Du Preez, L.H., N. Kunene, R. Hanner, J. P. Giesy, K.R. Solomon, A. Hosmer and G.J. Van Der Kraak. 2009. Population-specific incidence of testicular ovarian follicles in Xenopus laevis from South Africa: A potential issue in endocrine testing. Aquatic Toxicology 95:10-16.

Solomon, K., J.A.Carr, L.H. du Preez, J.P.Giesy, R.J. Kendall, E.E. Smith and G. Van Der Kraak. 2008. Effects of atrazine on fish, amphibians and aquatic reptiles: a critical review. Critical Reviews in Toxicology 38: 721-772.

Du Preez, L.H., N. Kunene, G.J. Everson, J.A. Carr, J.P. Giesy, T.S. Gross, A.J. Hosmer, R.J.Kendall, E.E. Smith, K.R. Solomon and G.J. Van Der Kraak, 2008. Reproduction, larval growth, and reproductive development in African Clawed frogs (Xenopus laevis) exposed to atrazine. Chemosphere 71: 546-552.

Park J.-W., M. Hecker, M.B. Murphy, P.D. Jones, K.R. Solomon, G. Van Der Kraak, J.A. Carr , E.E. Smith, L.H. du Preez, R.J. Kendall and J.P. Giesy. 2006. Development and optimization of a Q-RT PCR method to quantify CYP19 mRNA expression in testis of male adult Xenopus laevis: Comparison with aromatase enzyme activity. Comparative Biochemistry and Physiology 144B: 18-28.

Murphy M. B., M. Hecker, K.K. Coady, A.R. Tompsett, P.D. Jones, J.L. Newsted, H.L. Wong, L.H. du Preez, K.R. Solomon, J.A. Carr, E.E. Smith, R.J. Kendall, G. Van Der Kraak and Giesy JP. 2006. Sediment TCDD-EQs and EROD and MROD Activities in Ranid Frogs from Agricultural and Nonagricultural Sites in Michigan (USA). Archives of Environmental Contamination and Toxicology 51:467-477.

Murphy M. B., M. Hecker, K.K. Coady. A.R. Tompsett, P.D. Jones, L.H. du Preez, G.J. Everson, K.R. Solomon, J.A. Carr, E.E. Smith, R.J. Kendall, G. Van Der Kraak, and J.P.Giesy. 2006. Atrazine concentrations, gonadal gross morphology and histology in ranid frogs collected in Michigan agriculture areas. Aquatic Toxicology. 76: 230-245.

Murphy M. B., M. Hecker K.K. Coady, A.R. Tompsett, E.B. Higley, P.D. Jones, L.H. du Preez, K.R. Solomon, J.A. Carr, E.E. Smith, R.J. Kendall, G. Van Der Kraak and J.P. Giesy JP. 2006. Plasma sex steroid concentrations, aromatase activities and GSI in ranid frogs collected from agricultural and non-agricultural sites in Michigan (USA). Aquatic Toxicology 77: 153-166.

Hecker, M., M.B. Murphy, K. K. Coady, D. L. Villeneuve, P.D. Jones, J.A. Carr, K.R. Solomon, E.E. Smith, G.J. Van Der Kraak, T. Gross, L.H. du Preez, R.J. Kendall and J.P. Giesy. 2006. Terminology of gonadal anomalies in fish and amphibians resulting from chemical exposures. Reviews of Environmental Contamination and Toxicology 187: 103-131.

Smith E. E,, L.H. du Preez, A. Gentles, K.R. Solomon, B. Tandler, J.A. Carr, G.J. Van Der Kraak, R.J.Kendall , J.P. Giesy and T.S. Gross. 2005. Assessment of laryngeal muscle and testicular cell types in Xenopus laevis (Anura Pipidae) inhabiting maize and non-maize growing areas of South Africa. African Journal of Herpetology 54: 69-76.

Jooste, A.M., L.H. Du Preez, J.A. Carr, J.P. Giesy , T.S. Gross, R.J. Kendall, E.E. Smith, G.J. Van Der Kraak and Solomon KR. 2005. Gonadal development of larval male Xenopus laevis exposed to atrazine in outdoor microcosms. Environmental Science and Technology 39: 5255-5261.

Hecker, M., J.-W. Park, M.B. Murphy, P.D. Jones, K.R. Solomon, G. Van Der Kraak, J.A. Carr, E.E. Smith, L. du Preez, R.J. Kendall and J.P. Giesy JP. 2005. Effects of atrazine on CYP19 gene expression and aromatase activity in testes and on sex steroid concentrations in plasma of male African clawed frogs (Xenopus laevis). Toxicological Sciences 86: 273-280.

Hecker M., W.J. Kim, J.W. Park, M.B. Murphy, D.L. Villeneuve, K.K. Coady, P.D. Jones, K.R. Solomon, G. Van Der Kraak, J.A. Carr, E.E. Smith, L. du Preez, R.J. Kendall and J.P. Giesy. 2005. Effects of estradiol and atrazine on plasma sex steroid concentrations, gonadal aromatase activity and ultrastructure of the testis in Xenopus laevis. Aquatic Toxicology 72: 383-396.

Du Preez, L.H, K.R. Solomon, J.A. Carr , J.P. Giesy, T.S. Gross, R.J. Kendall, E.E. Smith, G. Van Der Kraak and C. Weldon. 2005. Population structure characterization of the clawed frog (Xenopus laevis) in maize-growing versus non-maize-growing areas in South Africa. African Journal of Herpetology 54: 61-68.

Du Preez L.H., P.J. Jansen van Rensburg, A.M. Jooste, J.A. Carr, J.P. Giesy, T.S. Gross, R.J. Kendall, E.E. Smith, G. Van Der Kraak, and K.R. Solomon. 2005. Seasonal exposures to triazine and other pesticides in surface waters in the western Highveld corn-production region in South Africa. Environmental Pollution 135: 131-141.

Hecker M., J.P. Giesy, P.D. Jones, A.M. Jooste, J.A. Carr JA, K.R. Solomon, E.E. Smith, G. Van Der Kraak, R.J. Kendall, L.H. Du Preez. 2004. Plasma sex steroid concentrations and gonadal aromatase activities in African clawed frogs (Xenopus laevis) from the corn-growing region of South Africa. Environmental Toxicology and Chemistry 23: 1996-2007.

Coady, K.K, M.B. Murphy, D.L. Villeneuve, M. Hecker, J.A. Carr, K.R. Solomon, G. Van Der Kraak , E.E. Smith, R.J. Kendall and Giesy JP. 2004. Effects of atrazine on metamorphosis, growth, and gonadal development in the green frog (Rana clamitans). Journal of Toxicology and Environmental Health Part A. 67: 941-957.

Carr, J.A., A. Gentles, E.E. Smith, W.L. Golman, L.J. Urquidi, K. Thuett, R.J. Kendall, J.P. Giesy, T.S. Gross, K.R. Solomon and G. Van Der Kraak. 2003. Response of larval Xenopus laevis to atrazine: Assessment of gonadal and laryngeal morphology. Environmental Toxicology and Chemistry 22: 396-405.