Welcome to the Gillis Lab. This lab, led by Professor Todd Gillis, is focused on the vertebrate heart and the mechanisms that regulate it’s function and ability to remodel in response to a physiological stressor.
Ultrasound image of functioning heart in live zebrafish
Current Projects
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Temperature induced cardiac remodeling in fish
There are a number of temperate fish species that remain active in the winter despite a decrease in environmental temperatures of at least 10 C. …
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Regulation of cardiac contractile function.
Images of a skinned trout cardiac trabeculae preparation mounted to the muscle mechanics system. (A) Trabeculae preparation attached to force transducer and servomotor using aluminium…
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Influence of bitumen exposure on Pacific salmon
The Trans Mountain Pipeline (TMP) carries crude oil products, including diluted bitumen (dilbit), through sensitive regions of the Fraser River Watershed (FRW), Canada’s largest salmon-bearing…
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Influence of hypoxia exposure on the cardiovascular system in fish.
Chronic hypoxia (30% O2 saturation) incubation from fertilization results in delayed development and growth in trout embryos. These two embryos are the result of the…
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The regulation of cardiac function in hagfish during anoxia exposure
Hagfish live at the bottom of the ocean where they spend considerable periods of time buried in the mud or within the putrefying carcasses of…
Encyclopedia of Fish Physiology, 2nd Edition, published in 2024. The Co-Editors and Chief are Drs Sarah Alderman and Todd Gillis while Drs Nick Bernier and Glen Van Der Kraak were Section Editors.
