Welcome to the Alderman Lab! We are integrative comparative physiologists who study a broad range of topics related to the regulation of neural, endocrine, and cardiac systems during stress. From brains to biomarkers, our goal is to understand the mechanisms and consequences of stressors on animal physiology. Current projects include:
- Mechanistic and functional connections between stress and adult neurogenesis in fish
- Effects of aquatic pollutants on fish physiology, morphology, and performance
- Neuroanatomy and regenerative capacity of the hagfish brain
- Quantitative proteomics as a tool for biomarker discovery and novel insights into animal physiology
Alderman Lab News
- November 2019. Congratulations Sean Avey on a successful MSc defense!
- June 2019. New paper published in Nature Scientific Reports by Sarah Alderman, Dane Crossley (North Texas), Ruth Elsey and Todd Gillis entitled: Hypoxia-induced reprogramming of the cardiac phenotype in American alligators (Alligator mississippiensis) revealed by quantitative proteomics.
- January 2018. New article written by Dr. Sarah Alderman on the sockeye and bitumen work published in the Conversation Canada
- December 2017. Project examining the consequence of bitumen exposure on salmon making national headlines Globe and Mail, CTV, CBC
- April 2017. New Article from the lab entitled “Proteomic analysis of sockeye salmon serum as a tool for biomarker discovery and new insight into the sublethal toxicity of diluted bitumen.” Authors are Drs. Sarah Alderman, Laura Dindia, Todd Gillis and our collaborators at Simon Fraser University and UBC.
- April 2017. New Article from the lab entitled “Novel insights into cardiac remodelling revealed by proteomic analysis of the trout heart during exercise training. Authors are Drs. Laura Dindia, Sarah Alderman and Todd Gillis
- November 2016. outside-jeb article published about Sarah Alderman’s recent paper: Effects of diluted bitumen exposure on juvenile sockeye salmon: From cells to performance
- June 2016. New paper published “Effects of diluted bitumen exposure on juvenile sockeye salmon: From cells to performance” Dr. Sarah Alderman, Feng Lin (SFU), Anthony P. Farrell (UBC), Christopher J. Kennedy (SFU) and Todd E. Gillis. Environmental Toxicology and Chemistry
- March 2016. New research paper by Dr. Sarah Alderman and UBC/Laurier colleagues featured in the Journal of Experimental biology. Title is “Evidence for a plasma-accessible carbonic anhydrase in the lumen of salmon heart that may enhance oxygen delivery to the myocardium”. Summary article here.
- Jan 2015. Article released today regarding sockeye salmon project in the lab.
- November 2014. New grant from NSERC ENGAGE to identify plasma biomarkers of cardiac stress in salmonid species. This project is being completed in collaboration with Cedarlane Labs.
- Sept 2014. New, three year grant from the Department of Fisheries and Oceans to study the influence of bitumen exposure on the cardiac health and fitness of sockeye salmon larvae. Co-Applicants are Dr. Todd Gillis (PI), Dr. Tony Farrell (UBC), Dr. Chris Kennedy (SFU) and Dr. Sarah Alderman (Guelph)