Welcome to the Alderman Lab! We are integrative comparative physiologists who study the effects of environmental stressors on neural, endocrine, and cardiac systems. From brains to biomarkers, our goal is to understand the mechanisms and consequences of stress on animal physiology. Current projects include:
- Mechanistic and functional connections between stress and adult neurogenesis in fish
- Effects of aquatic pollutants on fish physiology, morphology, and performance
- Neuroanatomy and regenerative capacity of the hagfish brain
- Quantitative proteomics as a tool for biomarker discovery and novel insights into animal physiology
Alderman Lab News
- January 2019. Alderman Lab receives funding from Great Lakes Fishery Commission to study blood biomarkers of sea lamprey parasitism in lake trout using quantitative proteomics: Towards a new tool for parasitic lamprey assessment – quantitative metrics of sea lamprey attack dynamics and host response.
- January 2019. New paper published in Aquatic Toxicology on the effects of bitumen on seawater acclimation in Atlantic salmon.
- November 2019. Congratulations Sean Avey on a successful MSc defense!
- July 2019. Heading to Seville for the Society for Experimental Biology conference. Check out my symposium with Dr. Matt Vickaryous: Brain Building: Plasticity in Form and Function of the Central Nervous System. #BrainsInSpain
- June 2019. New proteomics paper published in Scientific Reports: Hypoxia-induced reprogramming of the cardiac phenotype in American alligators (Alligator mississippiensis) revealed by quantitative proteomics.
- January 2019. New paper with collaborator Dr. Katie Gilmour (U Ottawa) and MSc student Jonathan Tea published in the Journal of Experimental Biology on social stress and neurogenesis in zebrafish.
- January 2018. New article written by Dr. Sarah Alderman on the sockeye and bitumen work published in the Conversation Canada
- December 2017. Project examining the consequence of bitumen exposure on salmon making national headlines: Globe and Mail, CTV, CBC
- April 2017. New article published in Comparative Biochemistry and Physiology D: Proteomic analysis of sockeye salmon serum as a tool for biomarker discovery and new insight into the sublethal toxicity of diluted bitumen.
- April 2017. New article published in the Journal of Proteomics: Novel insights into cardiac remodelling revealed by proteomic analysis of the trout heart during exercise training.
- November 2016. outside-jeb article published about Sarah Alderman’s recent paper: Effects of diluted bitumen exposure on juvenile sockeye salmon: From cells to performance
- June 2016. New paper published in Environmental Toxicology and Chemistry: Effects of diluted bitumen exposure on juvenile sockeye salmon: From cells to performance
- March 2016. New research paper by Dr. Sarah Alderman and UBC/Laurier colleagues featured in the Journal of Experimental biology: Evidence for a plasma-accessible carbonic anhydrase in the lumen of salmon heart that may enhance oxygen delivery to the myocardium. Summary article here.
- Jan 2015. Article released today regarding sockeye salmon project in the lab.
- November 2014. New grant from NSERC ENGAGE to identify plasma biomarkers of cardiac stress in salmonid species. This project is being completed in collaboration with Cedarlane Labs and Dr. Todd Gillis.
- Sept 2014. New, three year grant from the Department of Fisheries and Oceans to study the influence of bitumen exposure on the cardiac health and fitness of sockeye salmon larvae. Co-Applicants are Dr. Todd Gillis (PI), Dr. Tony Farrell (UBC), Dr. Chris Kennedy (SFU) and Dr. Sarah Alderman (Guelph)